A steroid sapogenin fromRuscus hyrcanus
نویسندگان
چکیده
منابع مشابه
Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus.
Diosgenin (3β-hydroxy-5-spirostene, 1), a plant-derived sapogenin, is used as a dietary supplement. However, the biological effects of 1 related to viral replication remain unexplored. In this study, the effects of 1 on hepatitis C virus (HCV) replication were evaluated. Based on a reporter-based HCV subgenomic replicon system, 1 was found to inhibit HCV replication at low micromolar concentrat...
متن کاملChildren with Steroid-resistant Nephrotic Syndrome: a Single-Center Study
Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...
متن کاملLaimaphelenchus hyrcanus n. sp. (Nematoda: Aphelenchoididae), a new species from northern Iran.
Laimaphalenchus hyrcanus n. sp., from bark samples of cypress (Cupressus sp.) and jujube (Ziziphus jujube Miller) from Gorgan, Golestan province in northern Iran, is described and illustrated based on morphological and molecular characters. The new species is characterized by females with 670-870 μm body length, slender stylet of 11-12 µm, six-lobed cephalic region not divided by ribs, three in...
متن کاملEffect of diosgenin, a steroidal sapogenin, on the rat skeletal system.
Diosgenin is a steroidal sapogenin present in fenugreek and Dioscorea spp. as glycosides (saponins). Diosgenin has already been reported to inhibit osteoclastogenesis and to stimulate osteogenic activity of osteoblastic cells in vitro, and to exert some antiosteoporotic effects in rats in vivo. The aim of the present study was to investigate the effects of diosgenin administration on the skelet...
متن کاملSteroid Flare Reaction; a Complication of Intraarticular Steroid Injection
A 63 year old man with bilateral knee osteoarthritis underwent an intraarticular steroid injection. After two days the patient developed severe pain and marked effusion in the left knee joint. Cultures were negative. He subsequently underwent bilateral knee replacement. The synovial biopsy of the left knee revealed marked granulation tissue and peculiar neutrophilic response against degenerated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1967
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00568000